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Abstract #8716 Published in IGR 5-1
Condition of ocular blood supply in patients with primary open-angle glaucoma with normal pressure
Kunin VDVestnik Oftalmologii 2003; 119: 10-13
The condition of discharge of intraocular fluid (IOF), the value of systemic arterial pressure (AP), the condition of mean dynamic arterial pressure in the ocular artery (Pm.ophth.), and the perfusion ocular pressure (Pperf.) were examined in patients with normal pressure glaucoma (NPG). A decrease in IOF discharge from 0.16 ± 0.02 mm3 per 1 mmHg at the initial stage of NPG to 0.11 ± 0.01 mm3 per 1 mmHg at the deteriorated stage of NPG was established. Decrease of systemic AP within an interval of 100-116 mmHg was observed in patients with NPG 6.9 times more often compared to controls (in 42.2 and 6.1% of cases, respectively). A reliable reduction of Pm.ophth. by 4.0 mmHg and of Pperf.--by 4.9 mmHg was found in patients with NPG compared to Pm.ophth. and Pperf. in controls with the same systemic AP values; the deficit of ocular volumetric blood flow reached 10.9%. The treatment of NPG patients must be related to improving IOF discharge, reducing genuine intraocular pressure to a tolerable level, and increasing systemic AP, Pm.ophth. and Pperf. to the mean statistically normal level.LA: Russian
Classification:
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
