advertisement
Abstract #8771 Published in IGR 5-1
The negative correlation between age and intraocular pressures measured nyctohemerally in elderly normal-tension glaucoma patients
Okada K; Tsumamoto Y; Yamasaki M; Takamatsu M; Mishima HKGraefe's Archive for Clinical and Experimental Ophthalmology 2003; 241: 19-23
PURPOSE: To evaluate the correlation between age and intraocular pressure (IOP) measured every three hours for 24 hours in older normal-tension glaucoma (NTG) patients. METHODS: Ninety consecutive patients suspected of having NTG on the basis of both visual field defect and disc appearance were hospitalized for the measurement of nyctohemeral IOP every three hours over a 24-hour period with a Goldmann tonometer after a four-week wash-out of any existing medication. Sixty-nine patients (76.7%) were diagnosed as having NTG. Sixty-nine eyes of 69 subjects were enrolled for this prospective, cross-sectional study. They were divided into two groups by age (cut-off between 59 and 60 years: group 1, under 60 years; group 2, over 60 years). The correlations between age and the mean, maximum and minimum IOP and IOP variation of the eight nyctohemeral IOP measurements nyctohemerally were evaluated for each group. The times of day at which the maximum and minimum IOPs were observed were recorded. RESULTS: Groups 1 and 2 consisted of 28 patients (age: 50.2 ± 6.1 years) and 42 patients (age: 70.3 ± 6.1 years) (p < 0.0001), respectively. Neither mean, maximum or minimum IOP nor the IOP variation was significantly different between the groups (all p values = 0.115). The mean, maximum and minimum IOP in group 2 were all correlated with age (n = 41; r = -0.516, p = 0.0004; r = -0.434, p = 0.004; r = -0.522, p = 0.0004, respectively), while none of those in group 1 was correlated with age (all p values
Dr. K. Okada, Department of Ophthalmology, Hiroshima University School of Medicine, 1-2-3 Kasumi, Minami-ku, 734-8551 Hiroshima, Japan. hkmishi@hiroshima-u.ac.jp
Classification:
6.1 Intraocular pressure measurement; factors affecting IOP (Part of: 6 Clinical examination methods)
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
