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Abstract #8631 Published in IGR 5-1
Evaluation of applanation resonator sensors for intra-ocular pressure measurement: results from clinical and in vitro studies
Eklund A; Linden C; Backlund T; Andersson BM; Lindahl OAMedical and Biological Engineering and Computing 2003; 41: 190-197
Glaucoma is an eye disease that, in its most common form, is characterized by high intra-ocular pressure (IOP), reduced visual field, and optic nerve damage. For diagnostic purposes and for follow-up after treatment, it is important to have simple and reliable methods for measuring IOP. Recently, an applanation resonator sensor (ARS) for measuring IOP was introduced and evaluated using an in vitro pig-eye model. In the present study, the first clinical evaluation of the same probe has been carried out, with experiments in vivo on human eyes. There was a low but significant correlation between IOPARS and the IOP measured with a Goldmann applanation tonometer (r = 0.40, p = 0.001, n = 72). However, off-center positioning of the sensor against the cornea caused a non-negligible source of error. The sensor probe was redesigned to have a spherical, instead of a flat, contact surface against the eye, and was evaluated in the in vitro model. The new probe showed reduced sensitivity to off-center positioning, with a decrease in relative deviation from 89 to 11% (1 mm radius). For normalized data, linear regression between IOP
Dr. A. Eklund, Department of Biomedical Engr./Inform., University Hospital of Umea, Umea, Sweden. anders.eklund.us@vll.se
Classification:
6.1 Intraocular pressure measurement; factors affecting IOP (Part of: 6 Clinical examination methods)
