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Abstract #8741 Published in IGR 5-1
Evaluation of vascular risk factors in primary open-angle glaucoma using Doppler sonography
Maricic Dosen V; Karaman Martinovic ZActa Medica Croatica 2002; 56: 99-102
Primary open angle glaucoma (POAG) is a syndrome of progressive optic neuropathy characterized by optic nerve head excavation and visual field defects. Poor correlation between intraocular pressure (IOP) and progression of glaucoma disease makes vascular mechanism the center of attention. With color Doppler sonography, quantification of blood flow changes in the vessels supplying the optic nerve head is possible. AIM: To examine the antiglaucomatous action of selective-blockers by color Doppler sonography. PATIENTS AND METHODS: Forty-four patients (88 eyes) were divided into two groups: group 1 was treated with selective beta-blockers and group 2 with nonselective beta-blockers. Vascular indices (RI, PI) were measured in the central retinal artery and posterior ciliary arteries. RESULTS: Decreased blood flow and increased vascular indices were found in both groups, with a statistically significant difference between group 1 and group 2. Blood flow velocity was higher and vascular indices were lower in group 1 (betoptic 0.5%) than in group 2 (timolol 0.5%). CONCLUSIONS: Beta-blockers, (selective betaxolol-calcium channel blockers) have more potent vasoactive and neuroprotective action. Color Doppler sonography is useful in the quantification of blood flow changes in the vessels in patients with POAG. LA: Serbo-Croatian-Roman
Dr. V. Maricic Dosen, Zavod za oftalmologiju Opca bolnica, Sveti Duh Sveti Duh 64 10000 Zagreb, Hrvatska.
Classification:
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
11.7 Treatment of bloodflow (Part of: 11 Medical treatment)
