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Abstract #8783 Published in IGR 5-1
Multifocal ERG recording with simultaneous fundus monitoring using a confocal scanning laser ophthalmoscope
Poloschek CM; Rupp V; Krastel H; Holz FGEye 2003; 17: 159-166
PURPOSE: To assess the general feasibility of recording multifocal electroretinograms (mfERGs) with simultaneous fundus monitoring in a clinical setting. METHODS: An mfERG system (RETIscan) and a confocal scanning laser ophthalmoscope (Heidelberg Retina Angiograph) were connected to record mfERGs elicited by a pseudorandom binary m-sequence stimulus generated by a 514 nm laser source. Recordings were compared to a conventional mfERG system using monitor stimulation. A total of five subjects (two normal subjects and three patients) were examined. RESULTS: In normal volunteers, records obtained by the fundus-monitored mfERG showed highest response densities in the central fundus area and a decrease of response amplitudes towards the periphery paralleling cone receptor density. However, compared to the monitor stimulation, the drop-off of amplitudes as a function of eccentricity was not as clearly defined. The responses obtained from patients with retinal diseases were diminished in the areas of retinal dysfunction. CONCLUSIONS: These preliminary findings indicate that the technique of laser stimulation in principle allows for topographic retinal recording. This method might be useful, for example, if the retinal position of the stimulus array is not centered onto the fovea, but rather deviates due to fixation problems. However, further improvement of the technique appears necessary before considering routine clinical application.
Dr. F.G. Holz, Department of Ophthalmology University of Heidelberg Im Neuenheimer Feld 400 69120 Heidelberg Germany. frank_holz@med.uni-heidelberg.de
Classification:
6.7 Electro-ophthalmodiagnosis (Part of: 6 Clinical examination methods)
