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1 General aspects (0)   1.1 Epidemiology (6)   1.2 Population genetics (19)   1.3 Pathogenesis (5)   1.4 Quality of life (5)   1.5 Glaucomas as cause of blindness (3)   1.6 Prevention and screening (2) 2 Anatomical structures in glaucoma (0)   2.1 Conjunctiva (0)   2.2 Cornea (3)   2.3 Sclera (1)   2.4 Anterior chamber angle (0)   2.5 Meshwork (8)     2.5.1 Trabecular meshwork (0)     2.5.2 Schlemms canal (0)     2.5.3 Scleral outlet channels (0)   2.6 Aqueous humor dynamics (6)     2.6.1 Production (0)     2.6.2 Outflow (0)       2.6.2.1 Trabecular meshwork (0)       2.6.2.2 Uveoscleral (0)     2.6.3 Compostion (0)   2.7 Episcleral veins and venous pressure (0)   2.8 Iris (2)   2.9 Ciliary body (6)   2.10 Lens (0)   2.11 Vitreous body (0)   2.12 Choroid, peripapillary choroid, peripapillary atrophy (3)   2.13 Retina and retinal nerve fibre layer (24)   2.14 Optic disc (23)   2.15 Optic nerve (0)   2.16 Chiasma and retrochiasmal central nervous system (3)   2.17 Stem cells (0)   2.20 Other (1) 3 Laboratory methods (10)   3.1 Microscopy (0)   3.2 Electron microscopy (0)   3.3 Immunohistochemistry (7)   3.4 Molecular genetics (1)     3.4.1 Linkage studies (0)     3.4.2 Gene studies (0)   3.5 Molecular biology incl. 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    9.4.1 Steroid-induced glaucoma (2)     9.4.2 Glaucomas associated with disorders of the cornea, conjunctiva, sclera (0)       9.4.2.1 Iridocorneal endothelial syndrome (ICE, incl. irisatrophy) (0)       9.4.2.2 Posterior polymorphous dystrophy (0)       9.4.2.3 Fuchs' endothelial dystrophy (0)       9.4.2.5 Other (0)     9.4.3 Glaucomas associated with disorders of the iris and ciliary body (0)       9.4.3.1 Pigmentary glaucoma (2)       9.4.3.5 Other (0)     9.4.4 Glaucomas associated with disorders of the lens (0)       9.4.4.1 Exfoliation syndrome (4)       9.4.4.2 Glaucomas associated with cataracts (2)       9.4.4.3 Glaucomas associated with lens dislocation (0)       9.4.4.5 Other (0)     9.4.5 Glaucomas associated with disorders of the retina, choroid and vitreous (0)       9.4.5.1 Neovascular glaucoma (3)       9.4.5.5 Other (0)     9.4.6 Glaucomas associated with inflammation, uveitis (0)     9.4.7 Glaucomas associated with ocular trauma (1)     9.4.8 Glaucomas associated with intraocular tumors (0)     9.4.9 Glaucomas associated with elevated episcleral venous pressure (2)       9.4.10 Glaucomas associated with hemorrhage (0)     9.4.11 Glaucomas following intraocular surgery (0)       9.4.11.1 Ciliary block (malignant) glaucoma (1)       9.4.11.2 Glaucomas in aphakia and pseudophakia (1)       9.4.11.3 Epithelial, fibrous, and endothelial proliferation (0)       9.4.11.4 Glaucomas associated with corneal surgery (1)       9.4.11.5 Glaucomas associated with vitreoretinal surgery (2)     9.4.15 Glaucoma in relation to systemic disease (10)     9.4.20 Other (0) 10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy (9) 11 Medical treatment (1)   11.1 General management, indication (4)   11.2 Cholinergic drugs (3)   11.3 Adrenergic drugs (1)     11.3.1 Epinephrine (0)     11.3.2 Thymoxamine, dapiprazole (0)     11.3.3 Apraclonidine, brimonidine (10)     11.3.4 Betablocker (14)     11.3.5 Other (0)   11.4 Prostaglandins (37)   11.5 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Without tube implant (5)     12.8.2 With tube implant or other drainage devices (10)     12.8.3 Non-perforating (8)     12.8.4 Using laser (1)     12.8.5 Other (0)     12.8.10 Woundhealing antifibrosis (20)     12.8.11 Complications, endophthalmitis (10)   12.9 Trabeculotomy, goniotomy (1)   12.10 Cyclodestruction (1)   12.11 Cyclodialysis (0)   12.12 Cataract extraction (0)     12.12.1 Intracapsular (0)     12.12.2 Extracapsular (1)     12.12.3 Phacoemulsification (4)   12.14 Combined cataract extraction and glaucoma surgery (0)     12.14.1 Intracapsular (0)     12.14.2 Extracapsular (0)     12.14.3 Phacoemulsification (5)   12.15 Capsulotomy (0)   12.16 Vitrectomy (0)   12.17 Anesthesia (0)   12.20 Other (2) 13 Therapeutic prognosis and outcome (0)   13.1 Prognostic factors (0)   13.2 Outcome (0)     13.2.1 IOP (0)     13.2.2 Visual field (0)       13.2.2.1 Progression (0)       13.2.2.2 Improvement (0)     13.2.3 Other (0) 14 Costing studies; pharmacoeconomics (0) 15 Miscellaneous (7)

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Abstract #8803 Published in IGR 5-1

In vivo pachymetry in normal eyes of rats, mice and rabbits with the optical low coherence reflectometer

Schulz D; Iliev ME; Frueh BE; Goldblum D
Vision Research 2003; 43: 723-728

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The aim of this study was to determine the central corneal thickness (CCT) in living rats, mice, and rabbits using a non-contact, high-speed optical low coherence reflectometer (OLCR) mounted on a regular slit lamp. Both eyes of eight male Wistar rats, eight male balb-c mice and eight male Japanese rabbits were measured. Each eye was measured twice (one measurement consists of 20 scans), the average calculated. Additionally, CCT was measured in rabbits using an ultrasound pachymeter. The mean CCT was: rats: 159.08 μm (SD ± 14.99 μm), mice: 106.0 μm (SD ± 3.45 μm) and rabbits: 356.11 μm (SD ± 14.34 μm). With the use of OLCR we were able to accurately measure the CCT of rats, mice and rabbits in vivo. This technique may prove useful in further refractive, pharmacological and glaucoma studies.

Dr. D. Goldblum, Department of Ophthalmology, University of Bern, Inselspital, Bern CH-3010, Switzerland. goldblum@vsao.ch

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Classification:

2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)

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