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The authors measured the retinal blood flow in 11 healthy volunteers and seven diabetic patients using a new laser Doppler velocimetry (Canon, CLBF100). They calculated the coefficient of variation (CV) for vessel diameter, blood velocity, and blood flow of retinal artery and vein, respectively. The measurement was performed using a standard procedure lasting about 30 minutes in six volunteers (group A), and less than 15 minutes in the remaining five (group B). Group B showed a significantly smaller CV for arterial velocity than group A. Diabetic patients showed significantly larger values for arterial velocity, venous velocity and venous flow than group B. The CV for arterial and venous blood flow ranged from 10 to 14% in normal persons and from 20-23% in diabetic patients. While there is a limitation in detecting small changes in retinal blood flow, the present findings suggest the clinical usefulness of this method.LA: Japanese
Dr. K. Kitanishi, Department of Ophthalmology, Izumiotsu Municipal Hospital, 16-1 Gejocho, Izumiotsu-shi, Osaka-fu 595-0027, Japan
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)